Wednesday, February 10, 2021

Semaglutide...

 


A drug, semaglutide, made by Novo Nordisk, already is marketed as a treatment for Type 2 diabetes. In a clinical trial published in the New England Journal of Medicine, researchers at Northwestern University in Chicago tested semaglutide at a much higher dose as an anti-obesity medication.

Nearly 2,000 participants, at 129 centers in 16 countries, injected themselves weekly with semaglutide or a placebo for 68 weeks. Those who got the drug lost  15 to 20 percent of their body weight, on average, compared.

The most effective treatment so far is bariatric surgery, which helps people lose 25 percent to 30 percent of body weight, on average.

Monday, February 8, 2021

Had it ..

 


Studies on people who were exposed to Covid and then recovered have shown that their antibodies remained pretty stable, and only dropped "modestly" after six or eight months. 

Another promising outcome: coronavirus-specific B and T cells (which work together to remember and destroy infections) also appear to increase and remain high after infection.

New research that hasn't been peer-reviewed yet found that people who have already had Covid tend to have higher antibody responses after their first dose of the mRNA vaccines than two doses of the vaccine in people who haven't had it. 

Some immunologists argue that people who've recovered from Covid should only need one dose of a vaccine.

There have been some anecdotal reports of Covid survivors experiencing more severe side effects  feeling achy, sick or even feverish  after the first dose of vaccinations. 

"That makes complete sense, and shows you that the immune system is really responding to [the virus] in a much more vigorous way,"

Sunday, February 7, 2021

Reactance...

 


Would you like an apple or a banana?”  “No, I want an orange!” 

This tendency to go against the grain is called psychological reactance (Brehm & Brehm, 1981). Reactance is usually activated when we feel that our freedom is threatened.  Reactance motivates us to protect our own beliefs and views, and sometimes, to do the opposite of what we’re being asked to do.

Individuals are predisposed to resist and oppose any influence perceived as a restriction on their autonomy. . Highly reactant individuals do not like to be told what to do, and they do not like anyone influencing them.

Not liking to be told what to do also varies by culture. For instance, the well-known American spirit of independence marks a cultural tendency to protect one’s freedom, alongside a strong drive to be autonomous. The issue of getting Americans to wear masks in the pandemic is a more recent, though certainly not singular, example of how many individuals in the U.S. want to choose what to do—not be told what to do.

In contrast, in more collectivistic cultures that tend to value the group over the individual, people tend to follow the rules without questioning their motives

Apart...

 



Nowadays people often have several romantic relationships throughout their lives. We date, we have boyfriends and girlfriends, and sometimes even multiple marriages. This means that relationships — the vast majority of relationships, in fact — end. 

People refer to any relationship that ended as a "failed" relationship. For example, you might hear somebody say "he had three failed marriages before ..." 

To  talk about romantic relationships in general, many people have had wonderful, fulfiling relationships that were very rewarding, where the partners respected each other, helped each other out, shared some experiences, and learned about themselves. 

Sometimes, because somebody had to move, or they grew apart, or someone changed, the relationship had to end. But this does not mean that the whole relationship was a failure. To look at all ended relationships as failures disrespects the joy and growth that many ended relationships bring people, and can give someone a negative and depressing outlook on their love life. 

Its ended not failed

Friday, February 5, 2021

Revere...

 


Be careful all, it seems that we didn't have domestic terrorists in the past 100 years. 
Just a thought.

Old Dog......

 







Researchers at Tokyo Medical and Dental University (TMDU) showed that melatonin’s metabolite AMK can enhance the formation of long-term memories in mice.  

    Memory of objects were tested after treatment with melatonin or two of its metabolites.       

 Older mice that normally performed poorly on the memory task showed improvements as dosage increased.     

The metabolite AMK was found to be the most important as melatonin failed to improve memory if it was blocked from metabolizing into AMK.

It now looks like melatonin marketers might have to do a rethink. In a new study, researchers led by Atsuhiko Hattori at Tokyo Medical and Dental University (TMDU) in Japan have shown that melatonin and two of its metabolites help memories stick around in the brain and can shield mice, and potentially people, from cognitive decline.

may be we can teach an ood dog a new trick.  Just a thought.

Falsifying...

 



Former FBI lawyer Kevin Clinesmith will not serve jail time for changing a document that backed a surveillance warrant of former Trump associate Carter Page during the early Russia investigation, a federal judge ruled on Friday.

He is the only defendant charged in the Durham investigation, which has looked closely at the FBI's work on the early Russia investigation, including Page's ties to Russia and others with ties to the Trump 2016 campaign.

Clinesmith was sentenced to serve 12 months probation and 400 hours of community service.

 He pleaded guilty last year to falsifying information in an email that wrongly said Page had not been a CIA source previously, as the FBI sought to renew a foreign surveillance warrant for Page in 2017.

 . Just a thought.