Linked..

 

Diabetes and Alzheimer’s disease are closely linked through shared biological mechanisms, leading some researchers to unofficially refer to Alzheimer's as "Type 3 diabetes". Research indicates that having type 2 diabetes significantly increases the risk—by approximately 50% to 100%—of developing Alzheimer's. 

The connection between these conditions is primarily driven by how the body and brain handle insulin and glucose: 

 Just as body tissues can become resistant to insulin in type 2 diabetes, brain cells can also lose their sensitivity to the hormone. This "brain diabetes" impairs the ability of neurons to use glucose for energy, which can lead to cell dysfunction and death.

• Insulin resistance is linked to the build-up of amyloid-beta and tau proteins, the hallmark signs of Alzheimer’s. Insulin and amyloid-beta are both broken down by the same enzyme (IDE); when insulin levels are too high, the enzyme is "distracted" by insulin, allowing toxic amyloid to accumulate.
•  Chronic high blood sugar damages both large and small blood vessels. In the brain, this reduced blood flow can starve cells of oxygen and essential nutrients, contributing to cognitive decline.
•  High blood sugar triggers chronic inflammation throughout the body and brain, which can damage brain cells and accelerate the progression of dementia.

Answer..

 

Sorry..

 

Liberal Supreme Court Justice Sonia Sotomayor issued an unusual apology Wednesday for critical remarks she made about the upbringing of one of her conservative colleagues, Justice Brett Kavanaugh.

“At a recent appearance at the University of Kansas School of Law, I referred to a disagreement with one of my colleagues in a prior case, but I made remarks that were inappropriate," Sotomayor said in a statement issued by the court. "I regret my hurtful comments. I have apologized to my colleague.”

Kavanaugh was in the majority, while Sotomayor dissented. The court has a 6-3 conservative majority.

Without mentioning him by name, Sotomayor on April 7 referenced Kavanaugh’s opinion, which sought to explain why he joined the majority, according to a Bloomberg Law report.

She then added, Bloomberg Law reported: “This is from a man whose parents were professionals. And probably doesn’t really know any person who works by the hour.”

Kavanaugh, who is white, grew up in the Maryland suburbs of Washington D.C., while Sotomayor, the first Latina to serve on the court, whose parents were from Puerto Rico, spent her childhood in a public housing project in the Bronx, New York City.

Comment:

Why did she choose Kavanaugh in particular?  Just a thought

Jump..

 

At the March 11, 2026, Politico New York Agenda Albany Summit, Hochul said New York needs high-net-worth residents to help support generous social programs. She also said people should go to Palm Beach and see who they can bring back home.  

Kathy Hochul is also facing renewed attention over something she said in 2022. During the 2022 campaign, Hochul said Republicans tied to ‘the era of Trump’ should ‘jump on a bus’ to Florida, a line critic are resurfacing now. 

That line is being replayed now because her tone has changed. Back then, the message was combative. Now, it is practical, with Hochul openly talking in public today about bringing wealthy New Yorkers back to strengthen the state’s tax base.

Palm Beach is not just a sunny punch line in this story. It stands in for a bigger migration trend, with wealthy Northeastern residents often linked to moves into Florida during and after the pandemic years. That matters because Florida has no personal income tax.  

NASA..

 

Swal-Well

 

Political strategist Mike Madrid told CNN that the Democratic Party is having a “come to Jesus's moment” following Rep. Eric Swalwell (D-CA) being hit with sexual misconduct allegations.

Madrid joined CNN’s Laura Coates noted that the accusations against Swalwell which he is denying, throw a major twist into California’s gubernatorial race where polls show Swalwell was a frontrunner for Democrats. She referenced a Politico poll showing Swalwell pulling 11%, with only Tom Steyer scoring more among Democrats.

 Swalwell was a frontrunner thanks to President Donald Trump painting him as a “leader of Trump resistance.” Swalwell has been accused of sexually assaulting staffers. One former staffer alleged the congressman raped her.

Eric Swalwell, the fiercest face of the Democratic resistance, was raised by Republicans in Dublin, California.

When asked later how he came to the other side, Eric said it wasn’t hard: “Democrats just had the better ideas.”

Comment:

Ideas.. just a thought.

Summer..

 

The Trump administration will temporarily lift summer gasoline regulations as prices at the pump near $4 a gallon amid the Iran war.

The emergency fuel waiver allows refiners and retailers to sell E15 gasoline, which is blended with 15% ethanol, over the summer, the U.S. Environmental Protection Agency (EPA) announced Wednesday.

Restrictions on selling E10 gasoline, which contains 10% ethanol, will also be temporarily lifted, according to the agency. Normally, federal rules require a switch to more costly summer blends from June 1 through Sept. 15 because gas with higher ethanol content can evaporate more easily in hot weather, contributing to air pollution.

EPA is working with our federal partners to reduce unnecessary costs and uncertainty and ensure that gas prices remain affordable for all Americans through the summer," EPA Administrator Zeldin said in the statement. "This emergency action will provide American families with relief by increasing fuel supply and consumer choice."

Amendment..

 

Comment:

The Dems, for four years, run all the stories of confidence, greatness, and ... about the Biden Administration, while the boarders were crossed illegally, the laws are broken, inflation skyrocketing by 10%, food shortage worldwide as a result of expanding sanctions on Russia and Russia oil.

Now the Dems, forgetting all, and trying to discredit and oppose everything with this current administration.   Just a thought.

Busy..

 

Desire..