A recent study found that taking non-steroidal anti-inflammatory drugs (NSAIDs) such ibuprofen or naproxen for joint pain due to osteoarthritis may actually increase inflammation.
All participants in the study had an MRI of the knee, initially and during a four-year follow-up, to track cartilage thickness, composition, and other measurements to evaluate arthritis progression.
The scientists found that long-term use of NSAIDs had no benefit, and joint inflammation and cartilage quality were worse at a four-year follow-up, compared to the control group.
“In this large group of participants, we were able to show that there were no protective mechanisms from NSAIDs in reducing inflammation or slowing down the progression of osteoarthritis of the knee joint.
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